One intriguing interconference matchup, two key South division games and a Justin Herbert-Lamar Jackson prime-time meeting highlight Week 12's Sunday slate of games.
The Bills (6-5) and their penchant for turning the ball over (19) head into Philadelphia to face an Eagles team that's a league-best 9-1 despite a minus-1 turnover differential.
In the AFC South, the Texans (6-4) host the Jaguars (7-3) with first place on the line. Houston won at Jacksonville 37-17 in Week 3.
In the NFC South, first place could belong to a sub-.500 team after New Orleans (5-5) travels to Atlanta (4-6) for the teams' first meeting of the year.